The Kansas City Chiefs bounced back from their first defeat of the season with a dramatic 30-27 win over the Carolina Panthers.

The reigning Super Bowl champions saw their run of 15 straight wins ended by the Buffalo Bills last week, but got back to winning ways thanks to star quarterback Patrick Mahomes.

After a late Chuba Hubbard touchdown and two-point conversion had made it 27-27, the Chiefs got the ball back with less than two minutes on the clock and a 33-yard run from Mahomes helped set up Spencer Shrader for a game-winning field goal.

Mahomes finished the game with 269 yards and three touchdowns, two of them to Noah Gray in the first half.

Running back Jahmyr Gibbs scored two touchdowns as the Detroit Lions beat the Indianapolis Colts 24-6 to improve their record to 10-1, matching that of the Chiefs.

David Montgomery also ran for a score before having to leave the game with a shoulder injury.

The Tampa Bay Buccaneers ended a four-game losing streak with a 30-7 win over the New York Giants, who “mutually agreed” to terminate the contract of quarterback Daniel Jones earlier this week.

Jones’ replacement Tommy DeVito was sacked four times while opposite number Baker Mayfield ran for a touchdown and completed 24 of 30 pass attempts for 294 yards.

Baker Mayfield leaps to score a touchdown
Tampa Bay Buccaneers quarterback Baker Mayfield leaps to score a touchdown against the New York Giants (Rich Schultz/AP)

Rachaad White, Bucky Irving and Sean Tucker also ran for touchdowns in a one-sided contest.

The Dallas Cowboys ended their five-game losing streak with a remarkable 34-26 win over the Washington Commanders, with 30 points scored in the final three minutes.

KaVontae Turpin’s 99-yard kick-off return for a touchdown looked to have sealed victory for the Cowboys, only for the Commanders to respond with a field goal before getting the ball back with 33 seconds remaining.

Wide receiver Terry McLaurin sprinted 86 yards through the Dallas defence for a touchdown, only for Austin Seibert to miss the extra point.

The Commanders tried an onside kick and Juanyeh Thomas returned it 43 yards for a touchdown.

Quarterback Tua Tagovailoa threw four touchdown passes as the Miami Dolphins cruised to a 34-15 win over the New England Patriots, while the Tennessee Titans pulled off a surprise 32-27 victory at the Houston Texans.

The Minnesota Vikings improved to 9-2 thanks to a 30-27 overtime win against the Chicago Bears, Parker Romo kicking the decisive field goal from 29 yards.